In IPF, bronchialepithelialcells of abnormalbronchioles in areas of bronchiolization and densefibrosisindicaterobustexpression of FGF1, FGFR3 and FGFR4.
In a handful of patients (5 out of 255) abnormalresults were obtained and explained by coexistingdiffuse or central tapetoretinal degeneration.
Twodaysprior to the consultation, an abdominalradiograph was done because the patient hadn't stooled in a week. Nosigns of obstruction and noabnormalaccumulations of stool were found.